DNA Synthesis Service
Custom Oligonucleotides Synthesis
Our advantages:
Premium quality & high purity
Quality and purity of all the oligonucleotides from KareBay are guaranteed with strict quality control system. KareBay Bio™ has various advanced synthesizer, such as BLP platform, which is mainly used with SpectraMax for high-throughput synthesis. Additionally, KareBay also has ABI 3900 and BioAutomation, which is mainly used for large-scale synthesis. Also, KareBay has various models of HPLC instruments to purify 50nmol – 50umol products once and the purity is 95% or above.
Short turnaround time & fast delivery
Standard oligonucleotides will be synthesized and dispatched with 2 working days. DSL/OPC purified oligonucleotides (≤ 60 bases) usually take 1-2 working days. For PAGE/ HPLC purified oligonucleotides, it usually costs 2-3 working days. Modified oligonucleotides will take 5-7 working days.
Diverse purification methods
DSL purification/ C18 desalination;
OPC purification;
PAGE purification;
HPLC purification
High stability
For synthesizing high OD oligonucleotides, KareBay uses freeze-drying technology. Compare with utilizing vacuum drying oven, the oligonucleotide products treated with freeze-drying technology have less damage and the lyophilized products can be stability stocked at -20°C for up to one year or reserved at 4°C for several months.
Various modification available
KareBay provides various high-quality fluorescent modification services, including dual-labeled fluorescent probes, rare bases, phosphorothioated oligos, phosphate groups, various fluorescent group modifications, biotin and digoxin.